Kieran Marmion and Bundee Aki have both been named in the Ireland team to play Argentina in Saturday's Guinness Series tie at the Aviva Stadium.
The Connacht pair will earn their 23rd and 11th Ireland caps respectively in a team which is captained by Rory Best.
He is joined in the front row by Cian Healy and Tadgh Furlong. Iain Henderson and James Ryan start at lock with Peter O'Mahony, Sean O'Brien and CJ Stander filling the backrow slots.
Kieran Marmion partners Jonathan Sexton at halfback with Bundee Aki and Robbie Henshaw at inside and outside centre respectively.
Jordan Larmour is named at fullback for his first start at Aviva Stadium. He is joined in the back three by Jacob Stockdale and Keith Earls.
The replacements for Saturday are Sean Cronin, Jack McGrath, Andrew Porter, Devin Toner, Dan Leavy, Luke McGrath, Joey Carbery and Andrew Conway.
The match will be live on RTE and Channel 4 IRELAND Team & Replacements (v Argentina, Guinness Series 2018, Aviva Stadium, Saturday, November 10, kick-off 6.30pm):
15. Jordan Larmour (St. Mary's College/Leinster) 7
14. Keith Earls (Young Munster/Munster) 70
13. Robbie Henshaw (Buccaneers/Leinster) 36
12. Bundee Aki (Galwegians/Connacht) 10
11. Jacob Stockdale (Ballynahinch/Ulster) 12
10. Jonathan Sexton (St. Mary's College/Leinster) 76 (vc)
9. Kieran Marmion (Corinthians/Connacht) 22
1. Cian Healy (Clontarf/Leinster) 81
2. Rory Best (Banbridge/Ulster) 111 (c)
3. Tadhg Furlong (Clontarf/Leinster) 26
4. Iain Henderson (Queens University/Ulster) 39
5. James Ryan (UCD/Leinster) 11
6. Peter O'Mahony (Cork Constitution/Munster) 50 (vc)
7. Sean O'Brien (UCD/Leinster) 51
8. CJ Stander (Shannon/Munster) 26
16. Sean Cronin (St. Mary's College/Leinster) 63
17. Jack McGrath (St. Mary's College/Leinster) 51
18. Andrew Porter (UCD/Leinster) 9
19. Devin Toner (Lansdowne/Leinster) 61
20. Dan Leavy (UCD/Leinster) 10
21. Luke McGrath (UCD/Leinster) 7
22. Joey Carbery (Clontarf/Munster) 13
23. Andrew Conway (Garryowen/Munster) 8